Opportunity Information: Apply for HT942526VRPTRA
The FY26 Vision Research Program Translational Research Award (TRA) is a Department of the Army (USAMRAA) grant opportunity under the Congressionally Directed Medical Research Programs that focuses on moving vision-related discoveries out of the early research stage and into something that is genuinely ready to be tested in people. The intent is translational: taking a promising finding and turning it into a practical product or deliverable, such as a new drug, a medical device, or a clinical practice guideline, with enough supporting evidence that a definitive clinical trial could begin during the award period or be ready to launch by the time the project ends. In other words, the program is looking for proposals that can credibly bridge the gap between discovery and real-world clinical testing, rather than exploratory work that is still trying to prove a basic concept.
The award can support several types of activities as long as they serve that translation goal. Applicants can propose preclinical development work, clinical research that advances readiness for trials, or even a pilot clinical trial designed to de-risk and inform a later, larger study. What it will not support is a full-scale clinical trial, so projects need to be sized and designed accordingly (for example, focusing on feasibility, dosing, device performance, initial safety signals, workflow validation, or other key steps that enable a later pivotal trial). Another central requirement is that the proposed research must fit within at least one of the FY26 VRP Focus Areas, meaning it needs to align with the program priorities for that year rather than being a general vision science proposal.
Several features of the announcement shape how teams should build their applications. If the project involves developing a drug or a device, the research team is expected to include regulatory approval expertise, reflecting an emphasis on practical advancement toward FDA or other relevant regulatory pathways. The opportunity also offers a Partnering Principal Investigator Option, which allows two PIs to lead together as an Initiating PI and a Partnering PI, supporting collaboration across disciplines or institutions when that is necessary to reach a translational endpoint. Applications will be evaluated through scored peer review criteria that cover the strength of the research idea and rationale, the research strategy and feasibility, the likely impact, the qualifications of the personnel, and a post-award transition plan that explains how the work will move forward after the grant (for example, into a definitive clinical trial, a regulatory submission, commercialization, or adoption into clinical guidance). After peer review scoring, there is also a programmatic review that looks at whether the application fits the intent of the TRA, how it complements the overall VRP portfolio, its relative impact, and its relevance to military health needs, which is a key framing element for Department of Defense medical research funding.
From an administrative standpoint, this is a discretionary grant (Funding Opportunity Number HT942526VRPTRA) in the science and technology/research and development category (CFDA 12.420). Eligibility is listed as unrestricted, which typically means the program is open to a broad range of applicant organizations rather than being limited to a narrow set of institution types. The opportunity is run by the Department of the Army, USAMRAA. The posted original closing date is November 12, 2026, and the listing indicates an expectation of one award, while the award ceiling is not specified in the provided source. One additional point worth noting is that the VRP may share FY26 TRA applications and their reviews with the National Eye Institute (NEI), which creates a potential secondary path for funding consideration outside the DoD program, depending on NEI interest and priorities.Apply for HT942526VRPTRA
- The Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoW Vision, Translational Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on 2026-05-05.
- Applicants must submit their applications by 2026-11-12. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Unrestricted.
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FY26 Vision Research Program (VRP) Translational Research Award (TRA) FAQs
What is the FY26 VRP Translational Research Award (TRA)?
The FY26 Vision Research Program Translational Research Award (TRA) is a Department of the Army (USAMRAA) funding opportunity under the Congressionally Directed Medical Research Programs. It supports vision-related projects that move beyond early discovery and are positioned to become practical, testable deliverables for use in people.
What is the main goal of this award?
The goal is translational progress: taking a promising vision-related finding and developing it into a product or deliverable that is genuinely ready for clinical testing. The program is looking for projects that can credibly bridge the gap between discovery-stage research and real-world clinical evaluation.
What kinds of deliverables does the program expect?
Examples of intended deliverables include a new drug, a medical device, or a clinical practice guideline. The key is that the deliverable is supported by enough evidence and development work to enable a definitive clinical trial to begin during the award period or be ready to launch by the time the project ends.
Does the TRA fund basic or exploratory vision science?
No. The announcement emphasizes that this is not meant for exploratory work that is still trying to prove a basic concept. Proposals should be framed around a clear translational pathway toward human testing rather than early-stage discovery.
What types of activities can be supported under this award?
The TRA can support preclinical development work, clinical research that advances readiness for trials, and pilot clinical trials that reduce risk and inform a later, larger study, as long as those activities serve the translational goal.
Are full-scale clinical trials supported?
No. The opportunity specifically notes that it will not support a full-scale clinical trial. Projects should be sized as enabling work, such as feasibility, dosing, device performance, early safety signals, workflow validation, or other steps that set up a later pivotal/definitive trial.
Can a pilot clinical trial be proposed?
Yes. A pilot clinical trial is allowable when it is designed to de-risk and inform a later, larger study and fits the overall intent of preparing for a definitive clinical trial.
Does my project have to match specific program priority areas?
Yes. The proposed research must fit within at least one of the FY26 VRP Focus Areas. The program is not intended for general vision science proposals that do not align with those stated priorities.
If my project involves a drug or device, are there special team requirements?
Yes. If the project involves developing a drug or a device, the research team is expected to include regulatory approval expertise, reflecting the program’s emphasis on practical advancement toward FDA or other relevant regulatory pathways.
What is the Partnering Principal Investigator option?
The opportunity includes a Partnering Principal Investigator Option that allows two PIs to lead the project together: an Initiating PI and a Partnering PI. This supports collaborations across disciplines or institutions when that structure is needed to achieve the translational endpoint.
How will applications be evaluated in peer review?
Applications will be evaluated through scored peer review criteria that include the strength of the research idea and rationale, the research strategy and feasibility, the likely impact, the qualifications of the personnel, and a post-award transition plan describing how the work will move forward after the grant.
What is a post-award transition plan, and why does it matter?
The post-award transition plan explains what happens after the award period and how the project will continue moving toward real-world use. The announcement gives examples such as progressing into a definitive clinical trial, preparing a regulatory submission, commercialization, or adoption into clinical guidance.
Is there a review step after peer review?
Yes. After scored peer review, applications undergo a programmatic review. This looks at fit with the intent of the TRA, how the proposal complements the overall VRP portfolio, relative impact, and relevance to military health needs.
How important is military health relevance for this opportunity?
Military health relevance is explicitly part of the programmatic framing for Department of Defense medical research funding. The programmatic review considers relevance to military health needs as a key element.
Who is the funding agency for this opportunity?
The opportunity is run by the Department of the Army through USAMRAA (U.S. Army Medical Research Acquisition Activity) under the Congressionally Directed Medical Research Programs.
What is the Funding Opportunity Number (FON) for the TRA?
The Funding Opportunity Number is HT942526VRPTRA.
What is the CFDA number and category listed for this grant?
The listing includes CFDA 12.420 and places the opportunity in the science and technology/research and development category.
Is this a discretionary grant?
Yes. The opportunity is described as a discretionary grant.
Who is eligible to apply?
Eligibility is listed as unrestricted, which typically indicates that a broad range of applicant organizations may apply rather than only a narrow set of institution types.
What is the application deadline?
The posted original closing date is November 12, 2026.
How many awards does the program expect to make?
The listing indicates an expectation of one award.
What is the maximum award amount (ceiling)?
The award ceiling is not specified in the provided information.
Can applications be shared with the National Eye Institute (NEI)?
Yes. The VRP may share FY26 TRA applications and their reviews with the National Eye Institute (NEI). This may create a potential additional path for funding consideration outside the DoD program, depending on NEI interest and priorities.
Does NEI sharing guarantee additional funding?
No. The information provided indicates only that sharing may occur and may create a potential secondary path for consideration. Any NEI funding would depend on NEI interest and priorities.
What kind of project endpoint is the TRA trying to reach by the end of the award?
The TRA is aiming for a point where a definitive clinical trial could begin during the award period or be ready to launch by the project end, supported by strong translational evidence and a clear plan for next steps.
What are examples of appropriately scoped trial-enabling work?
Examples mentioned include feasibility testing, dosing work, device performance evaluation, capturing initial safety signals, workflow validation, and other critical steps that enable a later pivotal or definitive trial.
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