Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required) | PA 24 175

Opportunity Information: Apply for PA 24 175

The NIH Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required), funding opportunity number PA 24-175, is a discretionary NIH grant designed to help early-stage and developing investigators move toward research independence. The core goal is to provide substantial protected time and structured mentorship for three to five years so an awardee can deepen their research expertise, strengthen their publication record, build new skills, and transition into an independent investigator role in the biomedical, behavioral, or clinical sciences. A key feature of this specific K01 version is that it is intended for applicants whose proposed research will include an independent clinical trial, meaning the candidate is expected to be responsible for leading and managing a clinical trial as part of the career development and research plan.

Across NIH Institutes and Centers, the K01 mechanism generally supports intensive, supervised career development, but the exact emphasis can vary by Institute or Center. In addition to the common use case of supporting promising researchers on a path to independence, some participating NIH components use the K01 to help individuals retrain into a new scientific area or re-enter the research workforce after a significant career interruption, such as time away due to illness or major family responsibilities. NIH also notes that separate K01 funding announcements may exist with a specific focus on enhancing diversity in the research workforce, which is distinct from this parent announcement.

Eligibility is broad at the organizational level and includes many types of U.S.-based entities, such as state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); and small businesses. The announcement also explicitly highlights additional eligible applicant types, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.

At the same time, the opportunity draws clear boundaries around foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations) are not eligible to apply as applicant organizations, and non-domestic components of U.S. organizations are also not eligible to apply. However, NIH foreign components are allowed when they meet the NIH Grants Policy Statement definition, which generally means certain parts of the project may be conducted outside the U.S. if well-justified and permitted under NIH policy, even though the applicant organization itself must be domestic.

From an administrative standpoint, the sponsoring agency is the National Institutes of Health, the instrument type is a grant, and the activity category is listed under a broad set of public-purpose areas including education and health (among others). The opportunity is associated with multiple CFDA (Assistance Listing) numbers spanning many NIH Institutes and Centers, reflecting that multiple NIH components can use this parent K01 announcement to make awards. The posting indicates an original closing date of May 7, 2027, and the opportunity was created on April 24, 2024. The award ceiling and expected number of awards are not specified in the provided summary, which is common for parent NIH announcements where budgets and award counts can vary by Institute, fiscal year, and applicant circumstances.

• The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.286, 93.307, 93.310, 93.313, 93.361, 93.398, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.865, 93.866, 93.879.
• This funding opportunity was created on 2024-04-24.
• Applicants must submit their applications by 2027-05-07.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PA 24 175

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