Opportunity Information: Apply for PA 17 118

The Reducing Health Disparities Among Minority and Underserved Children (R01) opportunity (Funding Opportunity Number PA-17-118) is a National Institutes of Health (NIH) discretionary grant designed to support research that directly aims to reduce health disparities affecting children, particularly those from minority and underserved populations. The program reflects a strong emphasis on early childhood development, recognizing that interventions and supports delivered early in life can shape long-term health trajectories and help prevent unequal outcomes from becoming entrenched across the lifespan. Awards are made through the NIH R01 mechanism, which typically funds hypothesis-driven, investigator-initiated research projects that can range from mechanistic studies to applied intervention work, depending on the project goals and scope.

A central focus of this funding opportunity is research that explains and addresses the complex, layered drivers of child health disparities. NIH is explicitly encouraging bio-behavioral work that integrates multiple influences rather than treating disparities as the result of a single factor. This includes biological contributors such as genetics, cellular processes, and organ-system functioning, alongside lifestyle and behavior-related factors that may affect health risk and resilience. The opportunity also calls for careful consideration of environmental influences, including both physical environments and family environments, as well as social factors such as peer relationships and social networks that can shape behavior, stress exposure, and access to support. In addition, applicants are encouraged to incorporate economic, institutional, cultural, and family influences, acknowledging that disparities often emerge from interacting systems such as poverty, neighborhood resources, school and healthcare practices, structural barriers, discrimination, and culturally mediated health beliefs and caregiving patterns.

Beyond studies that seek to understand causes and pathways, the announcement also prioritizes research tailored to children who already have a known health condition and/or disability. In this area, the emphasis is on health promotion needs that may be different for children managing chronic illness, developmental conditions, or functional limitations, especially when those children also experience disadvantage tied to race, ethnicity, geography, or socioeconomic status. Projects might focus on improving disease management, reducing secondary complications, improving quality of life, strengthening family capacity to support care, or addressing access gaps that disproportionately affect underserved children with special healthcare needs.

The opportunity further highlights intervention-oriented work that tests, evaluates, translates, and disseminates prevention and health-promotion strategies. Importantly, NIH is open to interventions delivered in both traditional settings (such as clinics, hospitals, and schools) and non-traditional settings (which can include community centers, faith-based organizations, early childhood programs, home-based services, or other community-based platforms). This emphasis signals interest not only in whether an intervention works under ideal conditions, but also whether it can be adapted for real-world contexts, implemented with fidelity, scaled, and sustained in the communities where disparities are most pronounced. Translation and dissemination components may include implementation research elements, community-engaged approaches, or strategies to improve uptake among systems that serve children and families.

Eligibility is broad and includes many types of public and private organizations. Eligible applicants listed include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; and federally recognized Native American tribal governments. The announcement also allows applications from public housing authorities and Indian housing authorities, as well as Native American tribal organizations that are not federally recognized tribal governments. Nonprofit organizations are eligible whether or not they hold 501(c)(3) status, and for-profit organizations (other than small businesses) and small businesses are also included. The opportunity explicitly names additional eligible applicant categories that reflect an intention to reach institutions and organizations closely connected to underserved communities, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISI). Faith-based and community-based organizations are also eligible, as are eligible agencies of the federal government, regional organizations, U.S. territories or possessions, Indian/Native American tribal governments other than federally recognized entities, and even non-U.S. (foreign) organizations.

From an administrative standpoint, the opportunity is categorized under Education and Health funding activities and is associated with CFDA numbers 93.173 and 93.361. It was created on 2017-01-09, and the original closing date listed is 2018-01-24. The source information does not specify an award ceiling or expected number of awards in the excerpt provided, so applicants would typically consult the full NIH funding announcement and any institute-specific guidance to understand budget expectations, project period norms, and review considerations.

Overall, this R01 opportunity is geared toward rigorous, multi-factor research that can clarify why disparities emerge in childhood and, just as importantly, test practical and scalable solutions. The strongest fit is work that ties disparities to interacting biological, behavioral, social, and structural influences, and that produces actionable evidence for prevention, health promotion, and improved outcomes for minority and underserved children, including those with existing health conditions or disabilities.

  • The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Reducing Health Disparities Among Minority and Underserved Children (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173, 93.361.
  • This funding opportunity was created on 2017-01-09.
  • Applicants must submit their applications by 2018-01-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Chronic Condition Self-Management in Children and Adolescents (R21) Apply for PA 17 116

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Funding Number: PAR 17 124
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Perception and Cognition Research to Inform Cancer Image Interpretation (R01) Apply for PAR 17 125

Funding Number: PAR 17 125
Agency: National Institutes of Health
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Quantitative Imaging Tools and Methods for Cancer Therapy Response Assessment (UG3/UH3) Apply for PAR 17 128

Funding Number: PAR 17 128
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Quantitative Imaging Tools and Methods for Cancer Response Assessment (U01) Apply for PAR 17 129

Funding Number: PAR 17 129
Agency: National Institutes of Health
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Innovations in Mechanisms and Interventions to Address Mental Health in HIV Prevention and Care Continuum (R21) Apply for PA 17 137

Funding Number: PA 17 137
Agency: National Institutes of Health
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Innovations in Mechanisms and Interventions to Address Mental Health in HIV Prevention and Care Continuum (R01) Apply for PA 17 136

Funding Number: PA 17 136
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NINR Clinical Trial Planning Grant (R34) Apply for PAR 17 133

Funding Number: PAR 17 133
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Funding Number: RFA NS 17 021
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Funding Number: PA 17 143
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Funding Number: PAR 17 150
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Mechanisms of Disparities in Chronic Liver Diseases and Cancer (R01) Apply for PAR 17 151

Funding Number: PAR 17 151
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Funding Number: PAR 17 152
Agency: National Institutes of Health
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Advancing our Understanding of the Brain Epitranscriptomics (R01) Apply for PAR 17 153

Funding Number: PAR 17 153
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Functional Genetics, Epigenetics, and Non-coding RNAs in Substance Use Disorders (R21) Apply for PA 17 157

Funding Number: PA 17 157
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Funding Number: PAR 17 159
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