Opportunity Information: Apply for CDC RFA GH19 1951
The grant opportunity titled "Strategic Information Support Across Countries under the Global Fund to Fight HIV/AIDS, Tuberculosis and Malaria and under the President's Emergency Plan for AIDS Relief (PEPFAR)" (Funding Opportunity Number: CDC RFA GH19-1951) is a Centers for Disease Control and Prevention (CDC) cooperative agreement designed to strengthen strategic information and monitoring and evaluation across PEPFAR-prioritized countries. In practical terms, the award is meant to help countries and implementing partners build stronger systems for tracking HIV and tuberculosis (TB) epidemics and program performance, so that decision makers can see what is happening in real time, fix problems quickly, and demonstrate measurable impact and accountability to funders and communities.
The core purpose of the NOFO is to reinforce strategic information activities tied to program and clinical monitoring and evaluation (M&E). It emphasizes improving the data foundations needed to run effective HIV and TB programs: surveillance systems that describe epidemic trends, monitoring systems that track service delivery and patient outcomes, health information systems that capture and connect data from clinics and laboratories, and statistical methods that turn raw data into reliable estimates and actionable insights. The overall intent is that better data and stronger analytic capacity will translate into more efficient patient management, clearer measurement of program results, and stronger accountability assessments across PEPFAR-supported efforts.
Funded activities are broad but center on improving how HIV and TB data are collected, managed, analyzed, and used. Examples include establishing or upgrading M&E systems and tools, assessing and strengthening national and subnational health information systems, and improving mapping approaches to understand where services are needed most and which populations are being missed. The NOFO also highlights program and laboratory data quality improvement work, which can include data quality assessments, routine data verification, standardization of indicators, and improving data flows between laboratories and clinical sites so that test results (such as viral load for HIV or diagnostic results for TB) are available quickly and correctly linked to the right patient record. Another major focus is enhanced monitoring and clinical cascade analysis, meaning the systematic review of how patients move through prevention, testing, treatment initiation, retention, and outcomes, and using those findings to close gaps.
A central theme is data use, not just data collection. The opportunity is geared toward helping countries and partners routinely use information for decision making, whether that is optimizing testing strategies, identifying facilities with retention challenges, targeting supportive supervision, or adjusting interventions for key populations. The NOFO explicitly ties these improvements to achieving the 95-95-95 goals, which depend heavily on knowing who has been diagnosed, who is on treatment, and who is virally suppressed, and being able to track those outcomes accurately across locations and over time.
Expected outcomes during the award period focus on lasting capacity improvements rather than one-off analyses. The CDC anticipates that recipients will help partners and host country counterparts implement or strengthen routine HIV and TB surveillance and M&E activities, improve data quality and data linkage across platforms, and increase the practical use of information for program management. Another expected outcome is better coordination between multiple data systems so patient-level information can be used in a timely way, including improved tracking for key populations where confidentiality, mobility, and stigma can complicate follow-up. Ultimately, the award is meant to improve the ability to measure the HIV response at global, national, and local levels by making data more accurate, connected, timely, and decision-relevant.
Administratively, this is a discretionary funding opportunity using a cooperative agreement mechanism, meaning CDC would typically have substantial involvement through technical collaboration and ongoing engagement rather than simply issuing funds and stepping back. The program sits within the health funding category and is associated with CFDA number 93.067. Eligibility is described as unrestricted, open to any type of entity that meets the requirements in the full announcement. The opportunity was created on August 13, 2018, with an original closing date of October 15, 2018 (applications due by 11:59 p.m. Eastern Time). The award ceiling listed is $10,000,000, and CDC expected to make two awards, indicating a limited number of recipients operating across multiple countries or regions to deliver targeted strategic information support at scale.Apply for CDC RFA GH19 1951
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Strategic Information Support Across Countries under the Global Fund to Fight HIV/AIDS, Tuberculosis and Malaria and under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Aug 13, 2018.
- Applicants must submit their applications by Oct 15, 2018 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $10,000,000.00 in funding.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQ)
What is the official title of this grant opportunity?
The opportunity is titled "Strategic Information Support Across Countries under the Global Fund to Fight HIV/AIDS, Tuberculosis and Malaria and under the President's Emergency Plan for AIDS Relief (PEPFAR)."
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is CDC RFA GH19-1951.
Which federal agency is offering this funding?
This is a Centers for Disease Control and Prevention (CDC) funding opportunity.
What type of funding mechanism is used?
The award uses a cooperative agreement mechanism. This typically means CDC expects to be substantially involved through technical collaboration and ongoing engagement, rather than only providing funds.
Is this a discretionary grant opportunity?
Yes. It is described as a discretionary funding opportunity.
What is the main purpose of the award?
The core purpose is to strengthen strategic information and program/clinical monitoring and evaluation (M&E) across PEPFAR-prioritized countries, so that HIV and TB programs can track epidemics and performance more effectively and use data for real-time decisions, accountability, and measurable impact.
What does "strategic information" mean in this NOFO?
In this context, strategic information refers to the systems, tools, and analytic methods used to collect, manage, link, analyze, and use HIV and TB data. This includes surveillance, routine monitoring, health information systems, and statistical approaches that produce reliable, decision-ready insights.
Which diseases and program areas are emphasized?
The opportunity focuses on HIV and tuberculosis (TB), with strategic information support aligned to PEPFAR-supported efforts and related Global Fund programming context.
What countries are the primary focus?
The award is designed to support PEPFAR-prioritized countries and implementing partners working across multiple countries or regions.
What kinds of activities does the NOFO expect recipients to support?
Activities are broad but centered on improving how HIV and TB data are collected, managed, analyzed, and used. Examples described include strengthening M&E systems and tools, improving surveillance and monitoring systems, enhancing health information systems, and upgrading analytic and estimation methods.
Does the opportunity include support for surveillance systems?
Yes. It emphasizes strengthening surveillance systems that describe epidemic trends and support routine HIV and TB surveillance activities.
Does the NOFO include improvements to health information systems (HIS)?
Yes. It highlights assessing and strengthening national and subnational health information systems, including better capture and connection of clinic and laboratory data.
Are mapping and geographic analyses part of the expected work?
Yes. The NOFO mentions improving mapping approaches to understand where services are needed most and which populations are being missed.
What does the NOFO say about data quality improvement?
Data quality improvement is a major focus. Examples include data quality assessments, routine data verification, standardization of indicators, and improving data flows so information is correct, consistent, and usable for decision making.
How does the NOFO address laboratory data?
It specifically calls out improving laboratory and program data quality and improving data flows between laboratories and clinical sites so test results (such as HIV viral load or TB diagnostic results) are available quickly and linked to the correct patient record.
What is meant by "data linkage across platforms" in this opportunity?
Data linkage refers to improving coordination and connection between multiple data systems so patient-level information can be combined and used in a timely way (for example, linking lab results with clinical records).
What is "enhanced monitoring" and "clinical cascade analysis" in practical terms?
It refers to systematically reviewing how patients move through key steps such as prevention, testing, treatment initiation, retention, and outcomes, then using those findings to close gaps in service delivery and patient care.
Is the goal mainly to collect more data or to use data better?
A central theme is data use, not just data collection. The NOFO is geared toward routine use of information for decision making and program management, such as adjusting interventions, targeting supportive supervision, and addressing performance problems quickly.
How does this opportunity connect to the 95-95-95 goals?
The NOFO ties strategic information improvements to achieving 95-95-95 by strengthening the ability to accurately track who has been diagnosed, who is on treatment, and who is virally suppressed across locations and over time.
What outcomes does CDC expect during the award period?
Expected outcomes emphasize lasting capacity improvements, including stronger routine HIV and TB surveillance and M&E, improved data quality and linkage, better coordination across systems, and increased practical use of information for program management and accountability.
Does the NOFO address key populations?
Yes. It notes the importance of timely patient-level tracking for key populations and recognizes that confidentiality, mobility, and stigma can complicate follow-up, making stronger data systems and coordination especially important.
What funding category is associated with this opportunity?
The opportunity sits within the health funding category.
What is the CFDA number associated with this award?
The CFDA number listed is 93.067.
Who is eligible to apply?
Eligibility is described as unrestricted, meaning it is open to any type of entity that meets the requirements described in the full announcement.
When was the opportunity created and when did it close?
It was created on August 13, 2018. The original closing date was October 15, 2018, with applications due by 11:59 p.m. Eastern Time.
What is the maximum award amount (award ceiling)?
The listed award ceiling is $10,000,000.
How many awards did CDC expect to make?
CDC expected to make two awards.
What does it imply that only two awards were expected?
Based on the description, it suggests a limited number of recipients would provide strategic information support at scale, likely operating across multiple countries or regions rather than in a single isolated setting.
What is the practical value of this grant for HIV and TB programs?
The practical aim is to help countries and partners build stronger systems that show what is happening in HIV and TB programs in near real time, enable faster troubleshooting, improve patient management, and strengthen accountability by producing more accurate, connected, and decision-relevant data.
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